He is the Director of C5Research, the Cleveland Clinic Coordinating Center for Clinical Research, an academic research organization which plans, coordinates, and manages multicenter clinical trials of new pharmacologic or device therapies. Dr. Lincoff’s research activities focus on development of therapies to reduce acute and long-term complications of percutaneous coronary revascularization procedures, to optimize therapy for acute coronary ischemic syndromes, or reduce progression or complications of atherosclerosis. He has served as principal investigator or steering committee member of over 20 pivotal trials in ischemic heart disease, enrolling in aggregate nearly 100,000 patients, studying new antithrombotic or metabolic agents in the settings of atherosclerosis or high cardiovascular risk, coronary intervention, heart attack, or unstable angina. Dr. Lincoff also supervises clinical research activities throughout the Cleveland Clinic as Director of the Center for Clinical Research and Vice Chairman for Clinical Research of the Lerner Research Institute. He is a Professor of Medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University. He holds the Charles and Charlotte Fowler Endowed Chair for Cardiovascular Research at the Cleveland Clinic. Dr. Lincoff has authored or coauthored over 300 peer-reviewed articles, including publications in the New England Journal of Medicine, Journal of the American Medical Association, Lancet, Annals of Internal Medicine, Circulation, Journal of the American College of Cardiology, American Heart Journal, and European Heart Journal. He has also authored over 80 book chapters and reviews and presented over 400 lectures at various medical meetings and courses throughout the world. He is the Consulting Editor of the American Journal of Cardiovascular Drugs and serves on editorial boards or as a reviewer for over 15 peer-reviewed scientific journals. Dr. Lincoff serves as the Chair of the Cardiovascular and Renal Drugs Advisory Committee of the United States Food and Drug Administration. Dr. Lincoff earned his undergraduate BS degree in chemical and biomedical engineering at Carnegie Mellon University in 1982 and his MD from Johns Hopkins University in 1986. He completed a residency in internal medicine at Beth Israel Hospital, Harvard Medical School, a fellowship in cardiovascular diseases at the University of Michigan Medical Center, and a fellowship in interventional cardiology at the Cleveland Clinic. He is a fellow of the American College of Cardiology and a member of the American Heart Association and the Sigma Xi Scientific Research Society.